AICAR

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a synthetic compound and research drug that activates AMP-activated protein kinase (AMPK). It is well known in sports science and medicine for its ability to mimic the metabolic effects of exercise.

 AICAR enters cells and acts as an analog to AMP, triggering AMPK. This pathway is a "master regulator" of cellular energy.When activated, AMPK promotes fat burning, glucose uptake in muscles, and the creation of new mitochondria, helping cells operate more efficiently under energy stress.